Detalhe da pesquisa
1.
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Cell
; 148(1-2): 244-58, 2012 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22265415
2.
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Mol Cell
; 47(2): 203-14, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22795131
3.
The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.
Genes Dev
; 26(14): 1546-57, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22802529
4.
Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.
Genes Dev
; 25(20): 2125-36, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21979375
5.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature
; 478(7370): 524-8, 2011 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21814200
6.
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.
Proc Natl Acad Sci U S A
; 109(23): 8971-6, 2012 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22615382
7.
FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer.
Target Oncol
; 18(2): 269-285, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826464
8.
Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators.
Nat Commun
; 10(1): 137, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635584
9.
Small interfering RNAs that trigger posttranscriptional gene silencing are not required for the histone H3 Lys9 methylation necessary for transgenic tandem repeat stabilization in Neurospora crassa.
Mol Cell Biol
; 25(9): 3793-801, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831483
10.
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Nat Commun
; 8: 15522, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28541300
11.
RNAi-dependent and RNAi-independent mechanisms contribute to the silencing of RIPed sequences in Neurospora crassa.
Nucleic Acids Res
; 32(14): 4237-43, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15302921
12.
BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.
Cancer Discov
; 6(6): 612-29, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099234
13.
The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells.
Cell Cycle
; 11(5): 1008-13, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22333593
14.
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence.
Cancer Cell
; 17(4): 376-87, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385362
15.
p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells.
Aging Cell
; 9(5): 736-46, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20569236
16.
Dissecting the senescence-like program in tumor cells activated by Ras signaling.
J Biol Chem
; 282(4): 2666-75, 2007 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-17135242
17.
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation.
Cell
; 126(3): 503-14, 2006 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16901784
18.
A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells.
J Biol Chem
; 280(29): 26776-87, 2005 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15908423